ABOUT THIS COURSE:
This is the last presentation in a six part, pre-recorded webinar series titled: Diabetes and Obesity Innovations: Applying the Latest Research to Clinical Applications. Type 2 diabetes affects over 23 million people in the United States and is directly responsible for over 115 billion dollars in annual health-care spending. The projected rates of diabetes are expected to double in developing countries over the next 40 years and researchers in basic and clinical sciences are conducting innovative studies designed to reduce the development and progression of diabetes. In this course, we will explore cutting edge research that has tremendous capacity to improve our understanding of diabetes and enhance our ability to educate patients with metabolic and cardiovascular disease. Since obesity is responsible for over 75% of the newly diagnosed cases of diabetes, we will provide an update on our current understanding of obesity and the development of novel nutritional and pharmacological approaches to affect energy balance. Obesity results from a chronic imbalance between energy intake and energy expenditure and is associated with decreased rates of vocational physical activity and the consumption of energy-dense foods. Caloric restriction and/or increases in physical activity are proven strategies for short-term body weight reduction. However, long-term success with caloric restriction and exercise interventions are poor and alternative nutritional and medical therapies are being explored to improve metabolic health. We will dissect the energy balance equation and present emerging evidence that convincingly demonstrates that alterations in nutrient composition or absorption can improve metabolic health without necessarily decreasing energy intake or increasing physical activity. Specifically, we will examine the role of essential amino acids, vitamins, minerals, plant polyphenols, and trace minerals on components of the energy balance equation. We will also examine the role of a novel group of hormones secreted by the stomach and gut which act in the brain to increase satiety and insulin sensitivity. Additional topics will focus on hormonal and nutritional signaling events that affect eating behavior and the activation of adipose tissue-derived factors which play crucial roles in energy metabolism. Finally, we will provide an overview of the concept of personalized medicine and how complementary and traditional medicine strategies can be used to individualize medicine.